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ChatGPT: Angel or Demond? Critical thinking is still needed
Mario Plebani
Diagnostic accuracy of Siemens SARS-CoV-2 Antigen (CoV2Ag) chemiluminescent immunoassay for diagnosing acute SARS-CoV-2 infection: a pooled analysis
Giuseppe Lippi, Brandon M. Henry, Mario Plebani
Neurofilament light chain as neuronal injury marker – what is needed to facilitate implementation in clinical laboratory practice?
Burak Arslan, Henrik Zetterberg
Clinical evidence requirements according to the IVDR 2017/746: practical tools and references for underpinning clinical evidence of IVD-MDs
Karine Charrière, Lionel Pazart
Potentials and pitfalls of ChatGPT and natural-language artificial intelligence models for the understanding of laboratory medicine test results. An assessment by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group on Artificial Intelligence (WG-AI)
Janne Cadamuro, Federico Cabitza, Zeljko Debeljak, Sander De Bruyne, Glynis Frans, Salomon Martin Perez, Habib Ozdemir, Alexander Tolios, Anna Carobene, Andrea Padoan
Detection of antinuclear antibodies: recommendations from EFLM, EASI and ICAP
Carolien Bonroy, Martine Vercammen, Walter Fierz, Luis E.C. Andrade, Lieve Van Hoovels, Maria Infantino, Marvin J. Fritzler, Dimitrios Bogdanos, Ana Kozmar, Benoit Nespola, Sylvia Broeders, Dina Patel, Manfred Herold, Bing Zheng, Eric Y.T. Chan, Raivo Uibo, Anna-Maija Haapala, Lucile Musset, Ulrich Sack, Gabor Nagy, Tatjana Sundic, Katarzyna Fischer, Maria-José Rego de Sousa, Maria Luisa Vargas, Catharina Eriksson, Ingmar Heijnen, Ignacio García-De La Torre, Orlando Gabriel Carballo, Minoru Satoh, Kyeong-Hee Kim, Edward K.L. Chan, Jan Damoiseaux, Marcos Lopez-Hoyos, Xavier Bossuyt, for the European Federation of Laboratory Medicine (EFLM) Working Group “Autoimmunity Testing,” the European Autoimmune Standardization Initiative (EASI) and International Consensus on Antinuclear Antibody Patterns (ICAP)
Analytical aspects of the antinuclear antibody test by HEp-2 indirect immunofluorescence: EFLM report on an international survey
Martine Vercammen, Carolien Bonroy, Sylvia Broeders, Edward K.L. Chan, Nicola Bizzaro, Dimitrios P. Bogdanos, Luis Andrade, Wim Coucke, Wilson de Melo Cruvinel, Ana Kozmar, Liisa Kuhi, Laurence Lutteri, Maria Jose Rego de Sousa, Sofie Schouwers, Lieve Van Hoovels, Xavier Bossuyt, on behalf of the EFLM Working Group on Autoimmunity Testing
Variability of cardiac troponin levels in normal subjects and in patients with cardiovascular diseases: analytical considerations and clinical relevance
A consensus document by the Study Group on Cardiac Biomarkers from Italian Society of Biochemical Chemistry (SIBioC) and European Ligand Assay Society (ELAS)
Aldo Clerico, Martina Zaninotto, Alberto Aimo, Daniela M. Cardinale, Ruggero Dittadi, Maria T. Sandri, Marco Alfonso Perrone, Lucia Belloni, Antonio Fortunato, Tommaso Trenti, Mario Plebani
Pre-analytical long-term stability of neopterin and neurofilament light in stored cerebrospinal fluid samples
Carolina Rosadas, Graham P. Taylor
Development of a candidate reference measurement procedure by ID-LC-MS/MS for total tau protein measurement in cerebrospinal fluid (CSF)
Chiara Giangrande, Hélène Vaneeckhoutte, Amandine Boeuf, Béatrice Lalere, Christophe Hirtz, Sylvain Lehmann, Milena Quaglia, Vincent Delatour
Assessing the commutability of candidate reference materials for the harmonization of neurofilament light measurements in blood
Ulf Andreasson, Johan Gobom, Vincent Delatour, Guy Auclair, Yoav Noam, Stephen Lee, Jason Wen, Andreas Jeromin, Burak Arslan, Aleksandra Maceski, Eline Willemse, Henrik Zetterberg, Jens Kuhle, Kaj Blennow
Surface plasmon resonance assays for the therapeutic drug monitoring of infliximab indicate clinical relevance of anti-infliximab antibody binding properties
Melina K. Grasmeier, Susanne Weber, Matthias Treiber, Markus A. Thaler, Peter B. Luppa
An antibody-free LC-MS/MS method for the quantification of sex hormone binding globulin in human serum and plasma
Bas Sleumer, Jordan Zwerwer, Martijn van Faassen, Michel J. Vos, Rainer Bischoff, Ido P. Kema, Nico C. van de Merbel
Accurate stratification between VEXAS syndrome and differential diagnoses by deep learning analysis of peripheral blood smears
Floris Chabrun, Valentin Lacombe, Xavier Dieu, Franck Geneviève, Geoffrey Urbanski
Establishing quality indicators for point of care glucose testing: recommendations from the Canadian Society for Clinical Chemists Point of Care Testing and Quality Indicators Special Interest Groups
Julie L.V. Shaw, Saranya Arnoldo, Lori Beach, Ihssan Bouhtiauy, Davor Brinc, Miranda Brun, Christine Collier, Elie Kostantin, Angela W.S. Fung, Anna K. Füzéry, Yun Huang, Sukhbir Kaur, Michael Knauer, Lyne Labrecque, Felix Leung, Jennifer L. Shea, Vinita Thakur, Laurel Thorlacius, Allison A. Venner, Paul M. Yip, Vincent De Guire
Clinical implication by differential analytical performances of serum free light chain quantitation analysis using fully automated analyzers
Shin Young Yun, John Hoon Rim, Hak Park, Hyein Kang, Sang-Guk Lee, Jong-Baeck Lim
Simultaneous analysis of antihyperglycemic small molecule drugs and peptide drugs by means of dual liquid chromatography high-resolution mass spectrometry
Aline C. Vollmer, Lea Wagmann, Armin A. Weber, Markus R. Meyer
Reference intervals for thyroid biomarkers to enhance the assessment of thyroid status in childhood and adolescence
Simona Ferraro, Ester Luconi, Valeria Calcaterra, Erika Cordaro, Alice Bianchi, Cristina Cereda, Gianvincenzo Zuccotti, Peter Kavsak, Mario Plebani, Elia Mario Biganzoli, Giuseppe Marano, Patrizia Boracchi
Biological variation of CA 15-3, CA 125 and HE 4 on lithium heparinate plasma in apparently healthy Caucasian volunteers
Louise Guillaume, Virginie Chapelle, Matthieu Deltombe, Arnaud Nevraumont, Antoine Mairesse, Diane Maisin, Damien Gruson
Individual risk prediction of high grade prostate cancer based on the combination between total prostate-specific antigen (PSA) and free to total PSA ratio
Simona Ferraro, Davide Biganzoli, Roberta Simona Rossi, Franco Palmisano, Marco Bussetti, Enrica Verzotti, Andrea Gregori, Filippo Bianchi, Marco Maggioni, Ferruccio Ceriotti, Cristina Cereda, Gianvincenzo Zuccotti, Peter Kavsak, Mario Plebani, Giuseppe Marano, Elia Mario Biganzoli
Using logistic regression models to investigate the effects of high-sensitivity cardiac troponin T confounders on ruling in acute myocardial infarction
Li Liu, Xueya Cai, Tanzy Love, Matthew Corsetti, Andrew M. Mathias, Andrew Worster, Jinhui Ma, Peter A. Kavsak
Assessment of humoral and cellular immunity after bivalent BNT162b2 vaccination and potential association with reactogenicity
Gian Luca Salvagno, Laura Pighi, Brandon M. Henry, Myriam Valentini, Beatrice Tonin, Damiano Bragantini, Gianluca Gianfilippi, Simone De Nitto, Mario Plebani, Giuseppe Lippi
Three rounds of a national external quality assessment reveal a link between disharmonic anti-SARS-CoV-2 antibody quantifications and the infection stage
Christoph Buchta, David Springer, Jovana Jovanovic, Christian Borsodi, Lisa Weidner, Nazanin Sareban, Ulla Radler, Mathias M. Müller, Andrea Griesmacher, Elisabeth Puchhammer-Stöckl, Thomas Wagner, Christof Jungbauer, Karin Stiasny, Lukas Weseslindtner
Where is laboratory medicine headed in the next decade? Partnership model for efficient integration and adoption of artificial intelligence into medical laboratories
Anna Carobene, Federico Cabitza, Sergio Bernardini, Raj Gopalan, Jochen K. Lennerz, Clare Weir, Janne Cadamuro
Please do not call it Theranos
Eleftherios P. Diamandis
Lot-to-lot bias for high-sensitivity cardiac troponin I concentrations ≥1000 ng/L
Peter A. Kavsak
Lot-to-lot reagent changes and commutability of quality testing materials for total bile acid measurements
Corey Markus, Suzette Coat, Hanns-Ulrich Marschall, Susan Matthews, Tze Ping Loh, Wayne Rankin, William M. Hague
On the importance of sampling interval in studies of biological variation in thyroid function
Stig Andersen, Johannes Riis, Jesper S. Karmisholt, Stine L. Andersen
Stability of plasma renin concentration based on plasma freezing time, as an adjunct to the stability data reported in the paper by Hepburn and others
Charlotte Oris, Damien Bouvier, Bruno Pereira, Adèle Saintonge, Anaïs Coelho, Vincent Sapin
Falsely low beta-hCG results in pregnant woman on Siemens Atellica: don’t forget the “hook effect”
Adrien Nizet, Philippe Jeanmart, Lucas Dewalque, Quentin Bodson
Proenkephalin A 119–159 (penKid) – a novel biomarker and its quantification on the Nexus IB10 POC system for assessing kidney function
Jared Cobb, Karolina Szczesna, Axel Schulze, Huy Ngo, McKenna Doyle, Tyler Do, Minh Vu, John Nguyen, Julia Löffler, Maryna Borshchivska, Deborah Bergmann, Elizabeth Shin, Tobias Hartmann, Damien Gruson
Investigating the polyuria-polydipsia syndrome: the “PP” Shiny app
Kay Weng Choy, Evangelia Georgiadis
Evaluation of a novel, stand-alone system to measure interleukin-6
Sascha Dierks, Mechthild Wiederhold, Julie Schanz, Andreas Fischer, Moritz Schnelle
Spurious low WBC count in the WNR channel of Sysmex XN-9000 hematology analyzer in a case with leukocyte aggregation
Qingkai Dai, Luyun Peng, Rui Shi
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